PUBLICATIONS

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Contractile pericytes determine the direction of blood flow at capillary junctions

Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):27022-27033. doi: 10.1073/pnas.1922755117.

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Microtubule structures underlying the sarcoplasmic reticulum support peripheral coupling sites to regulate smooth muscle contractility.

Sci Signal. 2017 Sep 19;10(497). pii: eaan2694. doi: 10.1126/scisignal.aan2694.

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Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow.

Nat Neurosci. 2017 May;20(5):717-726. doi: 10.1038/nn.4533. Epub 2017 Mar 20.

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Localized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilation.

Sci Signal. 2015 Jan 6;8(358):ra2. doi: 10.1126/scisignal.2005659.

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Vascular TRP channels: performing under pressure and going with the flow.

Physiology (Bethesda). 2014 Sep;29(5):343-60. doi: 10.1152/physiol.00009.2014.

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A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

Sci Signal. 2014 May 27;7(327):ra49. doi: 10.1126/scisignal.2004732.

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Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes.

PLoS One. 2014 Nov 3;9(11):e110996. doi: 10.1371/journal.pone.0110996. eCollection 2014.

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Ca(V)3.2 channels and the induction of negative feedback in cerebral arteries.

Circ Res. 2014 Sep 12;115(7):650-61. doi: 10.1161/CIRCRESAHA.114.304056. Epub 2014 Aug 1.

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Calcineurin/NFAT-Coupled TRPV4 Ca2+ Sparklets Stimulate Airway Smooth Muscle Cell Proliferation

Zhao, L., Sullivan, M.N., Chase, M., Gonzales, A.L., Earley, S

Am J Respir Cell Mol Biol. 2014 Jun;50(6):1064-75. doi: 10.1165/rcmb.2013-0416OC.

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Regulation of Cerebral Artery Smooth Muscle Membrane Potential by Ca2+-activated Cation Channels.

Gonzales, A.L., and Earley, S.

Microcirculation. 2013 May;20(4):337-47. doi: 10.1111/micc.12023. Review.

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Endogenous Cytosolic Ca2+ Buffering is Necessary for TRPM4 Activity in Cerebral Artery Smooth Muscle Cells

Gonzales, A.L., and Earley, S.

Cell Calcium. 2012 Jan;51(1):82-93. doi: 10.1016/j.ceca.2011.11.004. Epub 2011 Dec 7.

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Basal protein kinase Cδ activity is required for membrane localization and activity of TRPM4 channels in cerebral artery smooth muscle cells.

Garcia Z.I., Bruhl A, Gonzales A.L., Earley S.

Channels (Austin). 2011 May-Jun;5(3):210-4. Epub 2011 May 1.

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Pharmacological Inhibition of TRPM4 Hyperpolarizes Vascular Smooth Muscle.

Gonzales, A.L., Garcia, Z.I., Amberg, G.C., Earley, S.

Am J Physiol Cell Physiol. 2010 Nov;299(5):C1195-202. doi: 10.1152/ajpcell.00269.2010. Epub 2010 Sep 8.

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Vasoconstriction Resulting From Dynamic Membrane Trafficking of TRPM4 in Vascular Smooth Muscle Cells.

Crnich, R., Amberg, G., Leo, M.D., Gonzales, A.L., Tamkun, M.M Jaggar, J.H., Earley, S.

Am J Physiol Cell Physiol. 2010 Sep;299(3):C682-94. doi: 10.1152/ajpcell.00101.2010. Epub 2010 Jul 7.

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Ca2+ Release from the Sarcoplasmic Reticulum is Required for Sustained TRPM4 Activity in Cerebral Artery Smooth Muscle Cells. 

Gonzales, A.L., Amberg, G.C., Earley, S.

Am J Physiol Cell Physiol. 2010 Aug;299(2):C279-88. doi: 10.1152/ajpcell.00550.2009. Epub 2010 Apr 28.

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A Dietary Agonist of TRPV3 Elicits Endothelium-Dependent Vasodilation.

Earley, S., Gonzales, A.L., Garcia, Z.I.

Mol Pharmacol. 2010 Apr;77(4):612-20. doi: 10.1124/mol.109.060715. Epub 2010 Jan 19.

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Reduction in TRPC4 expression specifically attenuates G-protein coupled receptor-stimulated increases in intracellular calcium in human myometrial cells.

Ulloa, A., Gonzales, A.L., Zhong, M., Kim, Y., Cantlon, J., Clay, C., Ku, C., Earley, S., Sanborn., B.M.

Cell Calcium. 2009 Jul;46(1):73-84. doi: 10.1016/j.ceca.2009.05.003. Epub 2009 Jun 11.

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Endothelium-Dependent Cerebral Artery Dilation Mediated by TRPA1 and Ca2+-Activated K+ Channels.

Earley, S., Gonzales, A.L., Crnich, R.

Circ Res. 2009 Apr 24;104(8):987-94. doi: 10.1161/CIRCRESAHA.108.189530. Epub 2009 Mar 19.

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Turnover rate of the γ-aminobutyric acid transporter GAT1.

Gonzales, A.L., Lee, W., Spencer, S.R., Oropeza, R.A., Chapman, J.V., Ku, J.Y., Eskandari, S.

J Membr Biol. 2007 Dec;220(1-3):33-51. Epub 2007 Nov 9.